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Infectious disease · Updated 2026-09-29

Myxomatosis in rabbits

A severe viral disease spread by biting insects and direct contact; often fatal in unvaccinated domestic rabbits.

Emergency veterinary attentionRabbits
Veterinarian vaccinating a healthy pet rabbit, with an insect-meshed outdoor run visible through the window

AI-generated editorial illustration of the subject; not a photograph of a specific animal, product or case.

Visual guide to warning signs including breathing difficulty, appetite loss, vomiting, mobility change, abnormal droppings and collapse
Changes in breathing, appetite, movement, digestion or alertness can need veterinary assessment. Collapse and breathing difficulty are emergencies.

Signs to watch for

  • Swollen eyes, nose and genitals
  • Pus-like eye discharge
  • Fever and lethargy
  • Loss of appetite
  • Breathing difficulty
  • Skin lumps

Causes and risk factors

Myxoma virus transmitted by fleas, mosquitoes and mites, or by contact with infected rabbits.

How veterinarians diagnose it

Usually based on the characteristic appearance; laboratory confirmation is possible.

Treatment and management

Supportive nursing, pain relief, assisted feeding and antibiotics for secondary infection. Vaccinated rabbits have far better survival.

Prevention

Annual vaccination, insect-proof housing, mosquito netting and prompt flea control for all pets in the home.

Outlook

Poor in unvaccinated rabbits; vaccinated rabbits usually develop a milder, survivable form.

Common questions

What are the signs of myxomatosis in rabbits?
Swollen eyes, nose and genitals; Pus-like eye discharge; Fever and lethargy; Loss of appetite; Breathing difficulty; Skin lumps.
What causes myxomatosis in rabbits?
Myxoma virus transmitted by fleas, mosquitoes and mites, or by contact with infected rabbits.
How is myxomatosis in rabbits diagnosed?
Usually based on the characteristic appearance; laboratory confirmation is possible.
How is myxomatosis in rabbits treated?
Supportive nursing, pain relief, assisted feeding and antibiotics for secondary infection. Vaccinated rabbits have far better survival.
Can myxomatosis in rabbits be prevented?
Annual vaccination, insect-proof housing, mosquito netting and prompt flea control for all pets in the home.
When should I contact a veterinarian?
Isolate the rabbit and call your vet immediately. Do not bring a suspected case into a waiting room without warning the practice.

Preparing for a myxomatosis in rabbits consultation

  1. Record when these signs began and how they changed: Swollen eyes, nose and genitals; Pus-like eye discharge; Fever and lethargy. Record appetite, water intake, toileting and any medicines or supplements.
  2. The listed urgency is emergency; worsening breathing, collapse, seizures or severe pain can make any situation an emergency. Ask the clinic rather than relying only on this category.
  3. Ask what else could explain the signs, which tests would change the plan and how discomfort will be managed. Symptoms alone cannot confirm this condition.
  4. Before going home, agree what to monitor, when to recheck and which signs mean calling sooner. Follow the individual treatment plan; do not copy another pet's prescription.

Educational reference, not an individual diagnosis or a verified professional review. Read our editorial policy.

Sources on this topic

Pages on this specific subject from recognised organisations. They are cited for further reading and do not mean the organisation has reviewed this page.

Guidance libraries and further reading

These organisations publish relevant guidance. Their links are further reading, not evidence that they have reviewed this page.

  • WSAVA — global veterinary guidelines on nutrition, vaccination, pain and dental care
  • AAHA — American Animal Hospital Association guidelines
  • PDSA — veterinary charity pet health advice