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Hormonal disease · Updated 2026-09-29

Cushing's disease in dogs

Excess cortisol production, usually from a small pituitary tumour, causing thirst, hunger, a pot-bellied shape and skin changes.

Prompt veterinary attentionDogs
Illustrative cover: A senior dog resting on a blanket with a water bowl

Illustrative cover using relevant category imagery; it does not depict the exact subject.

Visual guide to warning signs including breathing difficulty, appetite loss, vomiting, mobility change, abnormal droppings and collapse
Changes in breathing, appetite, movement, digestion or alertness can need veterinary assessment. Collapse and breathing difficulty are emergencies.

Signs to watch for

  • Drinking and urinating much more
  • Ravenous appetite
  • Pot-bellied appearance
  • Hair loss on the body
  • Thin skin and slow healing
  • Panting and lethargy

Causes and risk factors

Most cases come from a benign pituitary tumour over-stimulating the adrenal glands; some arise from an adrenal tumour or long-term steroid medication.

How veterinarians diagnose it

Blood screening followed by specific hormone stimulation or suppression tests; imaging may locate the source.

Treatment and management

Daily medication to control cortisol production is the usual approach, with regular blood monitoring. Adrenal tumours may be surgical candidates.

Prevention

Not preventable, but early testing when the classic signs appear limits complications.

Outlook

Most dogs respond well to treatment and regain quality of life, though medication and monitoring are lifelong.

Common questions

What are the signs of cushing's disease in dogs?
Drinking and urinating much more; Ravenous appetite; Pot-bellied appearance; Hair loss on the body; Thin skin and slow healing; Panting and lethargy.
What causes cushing's disease in dogs?
Most cases come from a benign pituitary tumour over-stimulating the adrenal glands; some arise from an adrenal tumour or long-term steroid medication.
How is cushing's disease in dogs diagnosed?
Blood screening followed by specific hormone stimulation or suppression tests; imaging may locate the source.
How is cushing's disease in dogs treated?
Daily medication to control cortisol production is the usual approach, with regular blood monitoring. Adrenal tumours may be surgical candidates.
Can cushing's disease in dogs be prevented?
Not preventable, but early testing when the classic signs appear limits complications.
When should I contact a veterinarian?
Never stop Cushing's medication suddenly. Lethargy, vomiting or loss of appetite on treatment needs same-day veterinary advice.

Preparing for a cushing's disease in dogs consultation

  1. Record when these signs began and how they changed: Drinking and urinating much more; Ravenous appetite; Pot-bellied appearance. Record appetite, water intake, toileting and any medicines or supplements.
  2. The listed urgency is prompt; worsening breathing, collapse, seizures or severe pain can make any situation an emergency. Ask the clinic rather than relying only on this category.
  3. Ask what else could explain the signs, which tests would change the plan and how discomfort will be managed. Symptoms alone cannot confirm this condition.
  4. Before going home, agree what to monitor, when to recheck and which signs mean calling sooner. Follow the individual treatment plan; do not copy another pet's prescription.

Educational reference, not an individual diagnosis or a verified professional review. Read our editorial policy.

Sources on this topic

Pages on this specific subject from recognised organisations. They are cited for further reading and do not mean the organisation has reviewed this page.

Guidance libraries and further reading

These organisations publish relevant guidance. Their links are further reading, not evidence that they have reviewed this page.

  • WSAVA — global veterinary guidelines on nutrition, vaccination, pain and dental care
  • AAHA — American Animal Hospital Association guidelines
  • PDSA — veterinary charity pet health advice